Pin-Lan Li Selected Research

Inflammasomes

1/2022	Exosome Biogenesis and Lysosome Function Determine Podocyte Exosome Release and Glomerular Inflammatory Response during Hyperhomocysteinemia.
1/2021	Release and Actions of Inflammatory Exosomes in Pulmonary Emphysema: Potential Therapeutic Target of Acupuncture.
1/2021	Contribution of podocyte inflammatory exosome release to glomerular inflammation and sclerosis during hyperhomocysteinemia.
1/2021	Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes.
1/2020	Reversal of Endothelial Extracellular Vesicle-Induced Smooth Muscle Phenotype Transition by Hypercholesterolemia Stimulation: Role of NLRP3 Inflammasome Activation.
12/2019	Endothelial acid ceramidase in exosome-mediated release of NLRP3 inflammasome products during hyperglycemia: Evidence from endothelium-specific deletion of Asah1 gene.
1/2019	Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Containing Pyrin Domain 3 Inflammasome Activation.
1/2019	D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway.
1/2019	Suppression of Glucagon-Like Peptide-1 Release by Inhibition of Intestinal NLRP3 Inflammasome Activation in Asc-/- and Nlrp3-/- Mice.
1/2019	Podocyte NLRP3 Inflammasome Activation and Formation by Adipokine Visfatin.

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Pin-Lan Li Research Topics

Disease

20	Hyperhomocysteinemia 01/2022 - 09/2002
18	Inflammation (Inflammations) 04/2021 - 05/2015
16	Hypoxia (Hypoxemia) 10/2021 - 07/2002
14	Hypertension (High Blood Pressure) 10/2021 - 01/2007
14	Sclerosis 01/2021 - 06/2006
13	Atherosclerosis 11/2019 - 01/2013
10	Obesity 01/2019 - 09/2010
7	Proteinuria 09/2014 - 04/2010
6	Albuminuria 09/2014 - 10/2011
5	Infections 01/2021 - 06/2014
5	Neointima 12/2019 - 05/2014
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 02/2011
4	Hypercholesterolemia 01/2020 - 05/2013
3	Neoplasms (Cancer) 01/2022 - 12/2005
3	Vascular Diseases (Vascular Disease) 05/2021 - 02/2015
3	Nephrotic Syndrome (Syndrome, Nephrotic) 04/2021 - 01/2020
3	Vascular System Injuries 01/2020 - 05/2010
3	Diabetes Mellitus 01/2019 - 12/2010
3	Fibrosis (Cirrhosis) 10/2018 - 06/2013
3	Chronic Renal Insufficiency 04/2018 - 06/2013
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 09/2010
2	Edema (Dropsy) 01/2021 - 06/2015
2	Hyperglycemia 12/2019 - 12/2016
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2017 - 01/2008
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2017 - 01/2016
2	Liver Cirrhosis (Hepatic Cirrhosis) 06/2016 - 06/2014
2	Arteritis 02/2015 - 05/2014
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Necrosis 04/2021
1	Emphysema 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Chronic Disease (Chronic Diseases) 01/2021
1	Anaplasmosis 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2021

Drug/Important Bio-Agent (IBA)

34	InflammasomesIBA 01/2022 - 07/2012
16	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2002
12	SaltsIBA 10/2021 - 06/2006
12	CeramidesIBA 01/2021 - 09/2009
9	NucleotidesIBA 01/2022 - 05/2014
8	Small Interfering RNA (siRNA)IBA 01/2017 - 01/2009
7	NLR ProteinsIBA 01/2018 - 07/2012
7	NADPH Oxidases (NAD(P)H oxidase)IBA 09/2014 - 09/2009
6	SodiumIBA 10/2021 - 11/2012
6	SphingolipidsIBA 05/2021 - 09/2010
6	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2021 - 11/2011
6	AcidsIBA 01/2021 - 11/2011
6	CholesterolIBA 01/2017 - 05/2013
5	AdipokinesIBA 01/2019 - 12/2010
5	LipidsIBA 04/2018 - 09/2009
5	HomocysteineIBA 01/2016 - 06/2006
5	Superoxides (Superoxide)IBA 06/2015 - 06/2003
4	Antihypertensive Agents (Antihypertensives)IBA 10/2021 - 01/2007
4	EnzymesIBA 10/2021 - 01/2017
4	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 10/2021 - 06/2013
4	Nicotinamide PhosphoribosyltransferaseIBA 01/2019 - 02/2011
4	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2018 - 06/2013
4	AlbuminsIBA 11/2017 - 04/2010
3	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019 - 01/2009
3	Oxidoreductases (Dehydrogenase)IBA 01/2017 - 06/2013
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 01/2013
3	NADP (NADPH)IBA 02/2014 - 01/2009
3	Transcription Factors (Transcription Factor)IBA 01/2014 - 05/2008
2	Acid CeramidaseIBA 01/2021 - 12/2019
2	Simvastatin (Zocor)FDA LinkGeneric 01/2017 - 01/2013
2	CollagenIBA 01/2017 - 06/2016
2	CytokinesIBA 12/2016 - 01/2015
2	oxidized low density lipoproteinIBA 01/2016 - 05/2013
2	EndocannabinoidsIBA 01/2016 - 06/2014
2	NAADP (nicotinic acid adenine dinucleotide phosphate)IBA 01/2016 - 06/2013
2	HMGB1 Protein (HMG1)IBA 12/2015 - 05/2015
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014 - 05/2008
2	Heme Oxygenase-1IBA 01/2014 - 05/2008
2	Cyclic ADP-Ribose (cADPR)IBA 06/2013 - 07/2002
2	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 05/2013 - 04/2010
2	Death Domain ReceptorsIBA 01/2013 - 05/2010
2	Nitric Oxide Synthase (NO Synthase)IBA 11/2012 - 05/2008
2	Angiotensin IIIBA 10/2011 - 02/2011
2	Hypoxia-Inducible Factor-Proline DioxygenasesIBA 05/2010 - 01/2007
2	Messenger RNA (mRNA)IBA 01/2007 - 06/2006
1	Pharmaceutical PreparationsIBA 01/2022
1	sphingosine kinaseIBA 01/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	3- (4- chlorophenyl)- adamantane- 1- carboxylic acid (pyridin-4-ylmethyl)amideIBA 01/2022
1	Nonesterified Fatty Acids (NEFA)IBA 01/2021
1	Desipramine (Pertofrane)FDA LinkGeneric 01/2021
1	Interleukin-18 (Interleukin 18)IBA 01/2021
1	Pancreatic Elastase (Elastase)IBA 01/2021
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2021
1	Desoxycorticosterone Acetate (DOCA)FDA Link 01/2021
1	SphingosineIBA 01/2021
1	TrehaloseIBA 12/2019
1	Adiponectin ReceptorsIBA 11/2019
1	AdipoRonIBA 11/2019

Therapy/Procedure

2	Transplantation 01/2016 - 11/2014
1	Electroacupuncture 01/2021
1	Acupuncture Points (Acupuncture Point) 01/2021
1	Punctures 01/2021
1	Tracheotomy 01/2021